You've acquired scholarly literature and clinical evidence and appraised or evaluated the sources you've found. It's now time to integrate that evidence with your own clinical expertise and knowledge of your patient's preferences, circumstances, and values. Research evidence by itself is not enough to determine or justify a treatment. Your clinical expertise, your assessment of the patient, and laboratory data, are also important components in determining what evidence from your research is applied to your patient.
Guyatt GH, Haynes R, Jaeschke RZ, et al. (2000). Users' guides to the medical literature: XXV. Evidence-based medicine: Principles for applying the Users' Guides to patient care. JAMA, 2(84), 290-1296. https://dx.doi.org/10.1001/jama.284.10.1290