Evidence-based practice (EPB) experts distinguish between background and foreground questions.
Background questions ask for general knowledge about a condition or thing.
Foreground questions ask for specific knowledge and often contain several concepts. These types of questions can usually be answered based on current research evidence on diagnosing, assessing, or treating patients, or on understanding the meaning or prognosis of their health problems. Foreground questions seek the specific information needed to make clinical decisions. Many health care professionals use PICO or PICO(T) to help develop their questions.
Many health care professionals use the acronym PICO(T) to help formulate clinical research questions for evidence-based practice.
A good clinical question will address most, if not all, of the PICO framework. The PICO process starts with a case scenario from which a question is constructed that is relevant to the case, and is phrased in such a way as to facilitate finding an answer. Once you have written down what you know so far for each part of PICO, you will have some keywords to use as you acquire research evidence through library resources.
There are several types of PICO questions, depending on the category of your research question. Your question may not include all of the PICO(T) components, but it will always include P (Patient, Population, or Problem). These question templates may be helpful in getting started.
In ____________ (Population), what is the effect of ______________ (Intervention) in comparison to (Comparative/alternative intervention) on ______ (Outcome) within ____________ (Timeframe)?
For__________________ (Population), does _________________ (Identifying tool or procedure) yield more accurate or more appropriate diagnostic/assessment information than ________________ (Comparative tool/procedure) about ____________ (Outcome)?
In ______________ (Population) does ________________ (Influence/exposure to disease or condition), relative to _________________ (Comparative disease/condition OR absence of the disease/condition) increase the risk of _____________ (Outcome)?
In _________ (Population), does ____________ (Influence/exposure/characteristic) compared to ______________ (Comparative influence/exposure OR lack of influence/exposure) increase the risk of _______________ (Outcome)?
In ____________________ (Population), how prevalent is ________________ (Outcome)?
What is it like for _________________ (Population) to experience (condition, illness, circumstance)? OR
What is the process by which ________________ (Population) copes with, adapts to, or lives with (condition, illness, circumstance)?
Polit, D. F and Beck, C. T. (2021) Nursing research: Generating and assessing evidence for nursing practice (11th ed.). Wolters Kluwer.